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Cancers | Free Full-Text | Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists
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Nucleo‐cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein | The EMBO Journal
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A distinct p53 target gene set predicts for response to the selective p53– HDM2 inhibitor NVP-CGM097 | eLife
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Cancers | Free Full-Text | Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists
![Cancers | Free Full-Text | Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists Cancers | Free Full-Text | Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists](https://www.mdpi.com/cancers/cancers-11-01014/article_deploy/html/images/cancers-11-01014-g005.png)
Cancers | Free Full-Text | Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists
![FBI-1 represses transcription of the ARF, Hdm2, and p21 genes of the... | Download Scientific Diagram FBI-1 represses transcription of the ARF, Hdm2, and p21 genes of the... | Download Scientific Diagram](https://www.researchgate.net/profile/Sung-Eun-Kim-7/publication/24041513/figure/fig1/AS:460852143890437@1486887121715/FBI-1-represses-transcription-of-the-ARF-Hdm2-and-p21-genes-of-the-p53-pathway-A.png)
FBI-1 represses transcription of the ARF, Hdm2, and p21 genes of the... | Download Scientific Diagram
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Reciprocal relationship p53-Hdm2. Cellular levels and transcriptional... | Download Scientific Diagram
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Silencing of hdm2 oncogene by siRNA inhibits p53-dependent human breast cancer | Cancer Gene Therapy
Epigenetic landscape is defined by HDM/HMT gene expression signature.... | Download Scientific Diagram
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Domain architecture of HDM2 gene. Mutations present in HDM2 selectants... | Download Scientific Diagram
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A, Schematic depicting complex formed between HA-tagged HDM2, p53 and... | Download Scientific Diagram
![A distinct p53 target gene set predicts for response to the selective p53– HDM2 inhibitor NVP-CGM097 | eLife A distinct p53 target gene set predicts for response to the selective p53– HDM2 inhibitor NVP-CGM097 | eLife](https://iiif.elifesciences.org/lax/06498%2Felife-06498-fig6-v3.tif/full/,1500/0/default.jpg)
A distinct p53 target gene set predicts for response to the selective p53– HDM2 inhibitor NVP-CGM097 | eLife
Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53 | Aging
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Domain architecture of HDM2 gene. Mutations present in HDM2 selectants... | Download Scientific Diagram
![A schematic model for the function of RPL6 in regulating the HDM2-p53... | Download Scientific Diagram A schematic model for the function of RPL6 in regulating the HDM2-p53... | Download Scientific Diagram](https://www.researchgate.net/publication/258203788/figure/fig7/AS:203083771584523@1425430352356/A-schematic-model-for-the-function-of-RPL6-in-regulating-the-HDM2-p53-circuit-In.png)
A schematic model for the function of RPL6 in regulating the HDM2-p53... | Download Scientific Diagram
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Frontiers | It's Getting Complicated—A Fresh Look at p53-MDM2-ARF Triangle in Tumorigenesis and Cancer Therapy
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A Regulatory Loop Composed of RAP80-HDM2-p53 Provides RAP80-enhanced p53 Degradation by HDM2 in Response to DNA Damage - ScienceDirect
![Domain architecture of HDM2 gene. Mutations present in HDM2 selectants... | Download Scientific Diagram Domain architecture of HDM2 gene. Mutations present in HDM2 selectants... | Download Scientific Diagram](https://www.researchgate.net/profile/Chandra-Verma-4/publication/236654863/figure/fig13/AS:669666179575820@1536672267605/Domain-architecture-of-HDM2-gene-Mutations-present-in-HDM2-selectants-displaying-in_Q320.jpg)